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Friday, December 04, 2009 (14:32:19)
Tags : Genes, Opium, Pain Killers, Opioids

Hurt by social snub? Blame your genes

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Washington: Have you ever felt upset about being socially snubbed? Your genes, not your friends, may be at fault. Scientists have long known that opium-like pain killers, called opioids, relieve not only physical pain, but also some forms of emotional stress.

Now, a new study reviewed by Markus Heilig shows that small differences in the gene for the opioid receptor can determine the intensity of people's responses to social rejection.

Researchers at the University of California in Los Angeles (UCLA) questioned people about their responses to social rejection, which is a form of emotional stress.

They also performed brain scans on people playing a video game in which they were excluded from tossing a ball with computer-generated players.

The results showed that people with a certain mutation in their opioid receptor reacted more strongly to social rejection than those with a normal opioid receptor.

Heilig says that "strengthening the conclusions from this study is the fact that a similar polymorphism [genetic difference] has independently arisen in the rhesus macaque."

The same portion of the brain that is responsible for the response to physical pain became activated as a result of social rejection, suggesting that, to our brains, emotions really can "hurt", says a UCLA release.

These results were published in Proceedings of the National Academy of Sciences. (IANS)
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