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Tuesday, February 23, 2010 (13:16:11)
Tags : Dolphins, Marine Biologist, Human Cervical Cancer

Dolphins can help scientists understand cervical cancer

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Washington: Dozens of test samples from dolphins show that they could help marine biologists clue in on human cervical cancers.

Marine mammals like dolphins are our close kins, but scientific knowledge of infectious diseases, particularly of viral origin, affecting these animals is limited, researchers say.

"We discovered that dolphins get multiple infections of papillomaviruses, which are known to be linked with cervical cancer in women," said a researcher.

"Dolphins are the only species besides humans that we know of that can harbour co-infections, or infections of multiple papillomavirus types, in the genital mucosa."

There are approximately 100 types of human papillomaviruses (HPV), and multiple-type infections of up to eight HPV types have been reported in humans, he said.

"Even more surprisingly, some virus groups have shown the ability to cross the marine-terrestrial ecosystem boundary -- from sea to land," he said.

"We have demonstrated at least one case of genetic recombination between viruses of human and marine mammals.

"So while it's exciting that dolphins can provide a unique window into the role of co-infection in human cervical cancer, we can't rule out that the next high risk virus, such as SARS, or West Nile, might actually come from the marine environment," he added.

"Why do people develop the disease, but dolphins don't? If we can figure out why, the human medical community might be very interested in how that information might be applied to human strategies for preventing the disease," he said.

No animals are harmed during collection of cell and tissue samples, although some are obtained from animals that have died of natural causes in the wild. (IANS)
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